Alvotech to invests $250M in the advancement of biosimilar monoclonal antibodies Alvotech, a robust new player in the field of biopharmaceuticals, today announced programs to get $250 million in the development and production of a portfolio of biosimilar monoclonal antibodies www . Alvotech's current biosimilar assets consist of follow-on versions of leading monoclonal antibodies molecules, which is taken to market by 2018. Headquartered in Reykjavik, Iceland, Alvotech is an independent sister organization of the multinational pharmaceuticals business, Alvogen. Alvogen presently marketplaces biosimilars in selected areas through alliances with other firms including Hospira and offers many pending marketing authorizations world-wide.
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After a median follow-up of 20 months, median progression-free survival was 8 a few months and median general survival was 17 a few months. The toxicity profile was consistent with that expected for every specific agent, say the researchers, with hypertension, anaemia, oral mucositis, exhaustion, elevated gamma-glutamyl transferase, pain and lowered platelet count the most common grade 3 or more toxicities. All rights reserved. Neither of the parties endorse or suggest any commercial products, services, or equipment.. Alternating sunitinib, everolimus not supported in advanced RCC By Shreeya Nanda, Senior medwireNews Reporter Australian researchers report an alternating routine of sunitinib and everolimus, although low-risk and feasible in individuals with advanced renal cell carcinoma , failed to meet the prespecified criteria for use or continued development.